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Discovery, Computational Modelling and Prediction of Novel Virucidal Polymers against SARS-CoV-2 About the Project An important aspect of managing fomite transmission is the knowledge and development of novel virucidal polymers to eliminate the problematic cross-infections. Recently, strong virion binding polymers were discovered via experimental high-throughput screening and computational virtual screening in our group. However, we found that virus binding and their inactivation at material surfaces are not related in the simple manner. In this research, a dual-function polymer, which we demonstrated binds virions strongly and speeds their inactivation upon contact, will be the lead. The minor structure changes will be made to create a polymer library for the virucidal screening against Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). The experimental data will be processed to develop predictive structure-activity relationship (SAR) for the discovery of novel virucidal po
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