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Lung-MAP研究二代测序分析晚期肺鳞癌(SWOG S1400)

SCI天天读  · 公众号  ·  · 2024-08-25 20:00
    

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SCI 25 August 2024 Lung-MAP Next Generation Sequencing Analysis of Advanced Squamous Cell Lung Cancers (SWOG S1400) (Journal of Thoracic Oncology, IF: 21.0) David Kozono, Xing Hua, Michael C. Wu, Khaled A. Tolba, Saiama N. Waqar, Konstantin H. Dragnev, Haiying Cheng, Fred R. Hirsch, Philip C. Mack, Jhanelle E. Gray, Karen Kelly, Hossein Borghaei, Roy S. Herbst, David R. Gandara, Mary W. Redman CORRESPONDENCE TO: dkozono@bwh.harvard.edu Introduction 简介 Squamous cell cancer (SqCC) is a lung cancer subtype with few targeted therapy options. Molecular characterization, i.e., by next generation sequencing (NGS), is needed to identify potential targets. Lung-MAP SWOG S1400 enrolled patients with previously treated stage IV or recurrent SqCC to assess NGS biomarkers for therapeutic substudies.       肺鳞状细胞癌(SqCC)是肺癌的一种亚型,且几乎没有靶向治疗选择。目前需要二代测序(NGS)来了解其分子表征,来鉴定潜在靶点。Lung MAP SW ………………………………

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