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01 45-50岁患者中结直肠癌筛查完成情况和结果:观察性研究 主要研究结果: • 共发放了267,732个粪便隐血试验(FIT)试剂盒:45-49岁/50岁=213928/53804 • 45-49岁患者的FIT完成率略高于50岁患者(38.9% vs. 37.5%;aRR=1.05,95%CI:1.04-1.06]) • 45-49岁患者的FIT阳性率更低(3.6% vs. 4.0%;aRR=0.91, 95%CI: 0.84-0.98) • 两组阳性FIT结果后接受结肠镜检查的比例相似 • 年轻组的腺瘤检出率较低(58.8% vs. 67.7%;aRR=0.88, 95%CI:0.83-0.95) • 两组高级组织学的腺瘤、伴有高度异型增生的息肉、无蒂锯齿状病变和CRC的检出率相似 参考文献: Levin TR, Jensen CD, Udaltsova N, Burnett-Hartman AA, Kamineni A, Chao CR, Schottinger JE, Ghai NR, Pocobelli G, White LL, Oliver M, Chowdhry H, Hixon BP, Badalov JM, Goldberg SR, Bradford SC, Quesenberry CP, Lee JK. Colorectal Cancer Screening Completion and Yield in Patients Aged 45 to 50 Years : An Observational Study. Ann Intern Med.
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