骨生物学进展：通过功能性抑制表达瘦素受体的骨骼细胞来预防和治疗种植体周围纤维化

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点击上方 蓝字 关注我们 Prevention and treatment of peri-implant fibrosis by functionally inhibiting skeletal cells expressing the leptin receptor 作者： Vincentius Jeremy Suhardi, Anastasia Oktarina, Mohammed Hammad, Yingzhen Niu, Qingdian Li, Andrew Thomson, Juan Lopez, Jason McCormick, Ugur M. Ayturk, Matthew B. Greenblatt, Lionel B. Ivashkiv, Mathias P. G. Bostrom & Xu Yang (Department of Orthopedic Surgery, Hospital for Special Surgery,Department of Joint Surgery, The Third Hospital of Hebei Medical University,Department of Orthopedics, Guangdong Provincial People's Hospital, Southern Medical University) 发表情况： Nat Biomed Eng.  2024 Jul 31.doi: 10.1038/s41551-024-01238-y 科学问题 种植体周围纤维化是假体种植失败和置换关节假体术后手术翻修的最常见原因，尽管许多研究试图阐明导致种植体周围纤维化的炎症途径，但形成种植体周围纤维组织的细胞组成仍然难以捉摸，其分子介质尚不 ………………………………