文章预览
小鼠 人类 B淋巴细胞祖细胞 Lin- CD117- Ly6- Ly6D+ IL-7 Ra+ Flt-3+ CD10+ CD34+ Pax5+ B1祖细胞 Lin- CD45R low CD19+ CD93+ -- B2祖细胞 Lin- CD45R+ CD19- CD93- -- Pre-Pro B cell Lin- CD45R+ CD19- CD24 low CD43+
CD93+ CD117- CXCR4+
FLt-3+ IL-7Ra+ IgM- CD117 low CD10+ CD34+ CD38+ Pax5+ 祖B细胞 Lin- CD45R+ CD19+ CD24 + CD43+ CD117 low IL-7Ra+ IgM- CD117 low CD10+ CD19+ CD20+ CD24+ CD34+ CD38+ CD93+ IL3R+
IL-7 Ra+ Pax5+ 前B细胞 Lin- CD45R+ CD19+ CD24 + CD43- IL-7Ra+ IgM- CD117- CD10+ CD19+ CD20+ CD24+ CD34- CD38+
CD93+ IL-3 R+
IL-4 Ra+ IL-7 Ra+ Pax5+ 未成熟B细胞 CD45R+ CD19+ CD23- CD24+ CD43- CD93+ IgD- IgM+ CD117- CD10+ CD19+ CD20+ CD21+ CD24+ CD27-
CD38+ CD40+
CD93+ IL-4 Ra+ IL-7 Ra B1a细胞 CD1d mid CD5+ CD19 high CD23- CD43+ -- B1b细胞 CD1d mid CD5- CD19 high CD23- CD43+ -- 过渡性B细胞 CD45R+ CD19+ CD24+ CD43- CD93+ IgM+ IgD low/+ (T1/T2) CD10 low CD5+ CD19+ CD20+ CD21+ CD23+ CD24+
CD27- CD38+
CD93+ TACI+
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