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本期胸小星将为大家带来 免疫调节可溶HLA-G和HLA-E与肺移植术后CLAD恶化及HCMV升高相关；体外清除NETs可恢复废弃猪肺功能，一起来看看吧！ 2017·EATTS 01 Immunomodulatory soluble HLA-G and HLA-E are associated with rapidly deteriorating CLAD and HCMV viremia after lung transplantation Laura M Kühner1, Sarah M Berger1, Mila Djinovic1, Philippe L Furlano1, Lisa M Steininger1, Anna-Lena Pirker1, Peter Jaksch2, Elisabeth Puchhammer-Stöckl1, Hannes Vietzen1 1 Center of Virology, Medical University Vienna, Vienna, Austria. 2 Division of Thoracic Surgery, Medical University of Vienna, Vienna, Austria. Objective: Plasma-soluble (s)HLA-G and sHLA-E are immunoregulatory proteins that balance the activation of NKG2A+ immune cells. In lung-transplant recipients (LTRs), dysregulated NKG2A+ natural killer cell responses may result in high-level human cytomegalovirus (HCMV) replication as well as chronic lung allograft dysfunction (CLAD), and especial
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