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合成生物学应用——细胞工厂 Trends Biotechnol. 2024 Dec
3:S0167-7799(24)00308-1. doi: 10.1016/j.tibtech.2024.10.017. 通过蛋白质工程创造新的代谢途径用于生物生产。 Creating novel metabolic pathways by protein engineering for
bioproduction. Zhou Y(1), Liu Y(1), Sun H(2), Lu Y(3). Author information: (1)Department of
Chemistry, University of Texas at Austin, Austin, TX 78712, USA. (2)Department
of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA.
(3)Department of Chemistry, University of Texas at Austin, Austin, TX 78712, USA;
Department of Molecular Biosciences, University of Texas at Austin, Austin, TX
78712, USA. Electronic address: yi.lu@utexas.edu. 细胞生物工厂通过代谢工程生产了多种天然产物,其中酶在复杂的代谢网络中发挥着重要作用。然而,这种生物转化的范围可能受到天然酶的能力的限制。为了扩大其应用范围,许多天然酶最近被设计用于激活非
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