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合成生物学应用——细胞工厂 Crit Rev Biotechnol. 2024 Aug 12:1-21. doi:
10.1080/07388551.2024.2383754. 基因组挖掘和合成生物学在天然产物发现和生物合成中的最新进展。 Recent advances in genome mining and synthetic biology for discovery
and biosynthesis of natural products. Wang M(1)(2), Chen L(1)(2), Zhang Z(3),
Wang Q(2). Author information: (1)School of Life
Sciences, Qufu Normal University, Qufu, China. (2)Key Laboratory of Engineering
Biology for Low-carbon Manufacturing, Tianjin Institute of Industrial
Biotechnology, Chinese Academy of Sciences, Tianjin, China. (3)Department of
Zoology and Physiology, University of WY, Laramie, Laramie, WY, USA. 天然产物长期以来一直是化工和制药生产的重要原料,主要是为药物的发现和开发提供优良的支架或中间体。在上个世纪,天然产物贡献了超过三分之一的治疗药物生产。然而,在过去的几十年里,从天然产物中生产药物的传统
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