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SCI 13 September 2024 Targeting the tumour vasculature: from vessel destruction to promotion （Nat Rev Cancer; IF:72.5） Guelfi S, Hodivala-Dilke K, Bergers G: Targeting the tumour vasculature: from vessel destruction to promotion. Nat Rev Cancer 2024. Correspondence to: k.hodivala-dilke@qmul.ac.uk; gabriele.bergers@kuleuven.be As angiogenesis was recognized as a core hallmark of cancer growth and survival, several strategies have been implemented to target the tumour vasculature. Yet to date, attempts have rarely been so diverse, ranging from vessel growth inhibition and destruction to vessel normalization, reprogramming and vessel growth promotion. Some of these strategies, combined with standard of care, have translated into improved cancer therapies, but their successes are constrained to certain cancer types. This Review provides an overview of these vascular targeting approaches and puts them into context based on our subsequent improved understanding of the tumour vasculature
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