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以下由机器智能翻译,仅供参考。 1. The utility of biomarkers in traumatic brain injuries in children: opportunities and challenges 生物标志物在儿童创伤性脑损伤中的应用: 机遇与挑战 Traumatic brain injury (TBI) is a potentially life-altering or life-ending condition that affects individuals of all ages and walks of life. There is emerging evidence in the adult TBI literature to suggest that biomarkers have the potential to both refine management and predict outcomes. By contrast, pediatric TBI research lags notably behind, largely due to ethical and logistical difficulties in conducting high-quality clinical research in this cohort. Furthermore, children are a developmentally dynamic population, which adds additional complexities to both bench and clinical research. This review summarizes the recent updates in the field of pediatric TBI research and highlights both the promises and challenges of the use of TBI biomarkers in children. 创伤性脑损
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