健康警钟敲响！NHANES 研究维生素D增加胆结石的发病率 | 文献解读+回修精解

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01 作者简介   宾楚轩  BHV16040 02 文章标题 The association between vitamin D consumption and gallstones in US adults: A cross-sectional study from the NHANES 美国成年人维生素D摄入量与胆结石之间的关联：来自美国国家健康与营养检查调查（NHANES）的一项横断面研究 03 文献精读视频 04 JIE-COS原则解读 05 部分讨论与回复 1、协变量  Comment 1  In Results section, the author mentioned "When vitamin D was analyzed using quartiles, with increased quartile of  dietary vitamin D (D2+D3) consumption （ VDC）, the incidence of gallstones increased, and the OR of Q2 (OR: 1.08, 95% CI: 0.89-1.32, p = 0.436) and Q3 (OR: 1.55, 95% CI: 1.28-1.87, p < 0.001) was higher than that of Q1." However, this analysis did not account for covariates. Subsequent adjustment for covariates revealed no statistical significance. Therefore, it is crucial to acknowledge that without covariate adjustment, a significant association was observed ………………………………