【学术报告】2019年11月8日，Prof. Jun Ding, 斯坦福大学医学院

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【主题】 Re-opening the Critical Period to Restore the Synaptic Plasticity for Motor Learning in Parkinson's Disease 【时间】 2019年11月8日，13:00-14:30 【地点】 北京大学吕志和楼B101 【报告人 】 Prof. Jun Ding Assistant Professor Department of Neurosurgery, and Neurology, Stanford University School of Medicine 【邀请人 】 于翔 教授 Abstract Dynamic adaptations in synaptic plasticity are critical for learning new motor skills and maintaining memory throughout life, which rapidly decline with Parkinson's disease (PD). Plasticity in the motor cortex is important for acquisition and maintenance of motor skills, but how the loss of dopamine in PD leads to disrupted structural and functional plasticity in the motor cortex is not well understood. Here we used mouse models of PD and two-photon imaging to show that dopamine depletion resulted in stru ………………………………