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Dr. Boarhead’s Summary of Global Updates on the 2019 Novel Coronavirus: 5 April 2021 1. bioRxiv: B.1.1.7 变异株的纤突蛋白出现八种变异。研究人员培养了多种新冠病毒毒株,各含其中一种变异,还有一株含全部八种变异。研究发现,与其他各毒株相比,含 N501Y 变异的毒株在仓鼠上呼吸道与人体气管细胞中复制更快,更容易在动物间传播。 ( 3 月 9 日) [关键信息] N501Y 变异或系 B.1.1.7 变异株肆虐的原因。 bioRxiv: B.1.1.7 carries eight changes in the virus’s spike protein. A bevy of SARS-CoV-2 strains was generated, each with one of the individual spike mutations in B.1.1.7, as well as one carrying all the eight. It was found that (1) strains with a mutation called N501Y replicated more quickly than other strains in the upper respiratory tracts of hamsters and in airway
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