不同的GWAS软件如何如何计算SNP的解释百分比（PVE）？

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大家好，我是飞哥。 这里，分享一下常用GWAS软件，比如GAPIT，GEMMA，GCTA是如何计算显著SNP解释百分比（PVE）的。 1. 参考文献 首先是这个论坛的内容：How to determine the percent phenotypic variation explained (PVE) by a selected SNP? ❝ Feofanova, Elena. (2020). Re: How to determine the percent phenotypic variation explained (PVE) by a selected SNP?. Retrieved from: https://www.researchgate.net/post/How_to_determine_the_percent_phenotypic_variation_explained_PVE_by_a_selected_SNP/5e1600dd661123743209bc17/citation/download. ❞ 里面介绍了计算方法： 其中参考的文献是： ❝ Shim, H., Chasman, D.I., Smith, J.D., Mora, S., Ridker, P.M., Nickerson, D.A., Krauss, R.M., and Stephens, M. (2015). A multivariate genome-wide association analysis of 10 LDL subfractions, and their response to statin treatment, in 1868 Caucasians. PLoS One 10, e0120758. ❞ 里面的附件1：Supplementary Information: S1: Computing proportion of var ………………………………