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SCI 31 August 2024 Circular RNA in cancer （Nature Reviews Cancer；IF：72.5） Conn, V.M., Chinnaiyan, A.M. & Conn, S.J. Circular RNA in cancer. Nat Rev Cancer 24, 597–613 (2024). https://doi.org/10.1038/s41568-024-00721-7 Corresponding author: Simon J. Conn , Flinders Health and Medical Research Institute, College of Medicine and Public Health, Flinders University, South Australia, Australia. e-mail: simon.conn@flinders.edu.au Abstract 摘要 Over the past decade, circular RNA (circRNA) research has evolved into a bona fde research feld shedding light on the functional consequence of this unique family of RNA molecules in cancer. Although the method of formation and the abundance of circRNAs can difer from their cognate linear mRNA, the spectrum of interacting partners and their resultant cellular functions in oncogenesis are analogous. However, with 10 times more diversity in circRNA variants compared with linear RNA variants, combined with their hyperstability in the cell,
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