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报告详情 报告人:Pro f. Matthew D. Disney The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology 注:本次报告为线下报告。 时间: 2024年9月20日(星期五)15:30 地点: 北京大学化学与分子工程学院百廿纪念报告厅(A204) 主请人:陈鹏 报告摘要 Sequence-based design of small molecules targeting RNA structure One major scientific challenge is to understand biological pathways and to exploit the targets within them for therapeutic development. Coding and non-coding RNAs both directly cause disease, whether by mutation or aberrant expression. Akin to proteins, RNA structure often dictates its function in health or dysfunction in disease. RNA, however, is generally not considered a target for small molecule chemical probes and lead medicines, despite its immense potential. The focus of our research program is to uncover fund
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