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以下由机器智能翻译，仅供参考。 1. The Effects of Dexmedetomidine on Pain-Related Outcomes in Craniotomy: A Systematic Review and Meta-Analysis 右美托咪定对开颅术中疼痛相关结局影响的系统评价和Meta分析 Craniotomy is associated with several undesirable effects including postoperative pain. This systematic review and meta-analysis aimed to evaluate evidence on the efficacy and safety of dexmedetomidine (DEX) for pain management in patients undergoing craniotomy. The results showed that the use of DEX was associated with lower pain intensity and less opioid use. Patients in the DEX group experienced fewer episodes of nausea and vomiting, agitation, and shivering but more episodes of bradycardia. There was no difference between DEX and control groups in other adverse events. 开颅手术会带来一些不良影响，包括术后疼痛。本系统评价和荟萃分析旨在评估右美托咪定 (DEX) 用于开颅手术患者疼痛管理的有效性和
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