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靶向蛋白降解（TPD）是一项革命性技术，它能够利用包括泛素-蛋白酶体和溶酶体途径在内的天然细胞过程，选择性地消除特定的相关蛋白质。TPD技术在治疗癌症、神经退行性疾病、自身免疫性疾病、炎症、病毒和细菌感染等各种疾病方面前景广阔。鉴于 TPD 有潜力克服小分子药物和生物制剂等传统药物模式所面临的挑战，它已赢得了全球学术界、制药业和投资者的极大关注。 Targeted protein degradation (TPD) stands as a revolutionary technology capable of selectively eliminating specific proteins of interest by leveraging natural cellular processes, including the ubiquitin-proteasome and lysosome pathways. TPD technology holds immense promise for the treatment of diverse diseases, ranging from cancer, neurodegenerative diseases, autoimmune disorders, inflammatory ailments, to viral and bacterial infections. Given its potential to overcome the challenges associated w
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