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合成生物学应用——细胞工厂 Biotechnol Adv. 2024 Sep 24;77:108456. doi:
10.1016/j.biotechadv.2024.108456. 生物工程肝素 : 生产技术的进步。 Bioengineered heparin: Advances in production technology. Sultana R(1), Kamihira M(2). Author information: (1)Department of
Chemical Engineering, Faculty of Engineering, Kyushu University, 744 Motooka,
Nishi-ku, Fukuoka 819-0395, Japan; Department of Biotechnology and Genetic
Engineering, Faculty of Science, Noakhali Science and Technology University,
Noakhali 3814, Bangladesh. (2)Department of Chemical Engineering, Faculty of
Engineering, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
Electronic address: kamihira@chem-eng.kyushu-u.ac.jp. 肝素是一种高硫酸化糖胺聚糖，被认为是一种不可或缺的抗凝剂，具有多种治疗应用，在医疗实践中已成为近一个世纪的支柱。其潜力超出抗凝，有望用于治疗炎症、癌症和COVID-19等感染性疾病。然而，由
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