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SCI 4 October 2024 In vivo dendritic cell reprogramming for cancer immunotherapy (Science, IF: 44.7) Ervin Ascic, Fritiof Akerstroms, Malavika Sreekumar Nair, André Rosa, llia Kurochkin, Olga Zimmermannova, Xavier Catena. Nadezhda Rotankova, Charlotte Veser, Michal Rudnik. Tommaso Ballocei, Tiffany Scharer, Xiaoli Huang, Mariade Rosa Torres, Emilie Renaud, Marta Velasco Santiago, Ozcan Met, David Askmyr, Malin Lindstedt, Lennart Greiff, Laure-Anne Ligeon, Irina Agarkova, Inge Marie Svane, Cristiana F, Piress, Fábio F. Rosa, Carlos-Filive Pereira Correspondence to: filipe.pereira@med.lu.se Immunotherapy can lead to long-term survival for some cancer patients, yet generalized success has been hampered by insufficient antigen presentation and exclusion of immunogenic cells from the tumor microenvironment. Here, we developed an approach to reprogram tumor cells in vivo by adenoviral delivery of the transcription factors PU.1, IRF8, and BATF3, which enabled them to present antigens as typ
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